In order to help you to decide which method will be necessary, here are the characteristics of both samples and all patterns (you may decide to cope with only one of them). All data was collected at room temperature :

Sample 1

Kindly supplied by Zhu Jianghai, Center for Analysis &  Measurement Fudan University Shanghai.

• Crystal system: monoclinic 
• Cell : a = 7.673A, b = 9.628 A, c = 7.077 A, beta = 106.28° 
• Space groups : P2₁/m or P2₁ 

• 3 conventional X-ray (Cu K-alpha) 
• Bragg Brentano 

• Filename: Zhu1.*
• Run on Rigaku D/max-B 
• Rotating Anode Cu 
• Wavelengths: 1.54056 and 1.54439 A 
• Generator Power: 120mA, 40KV 
• Goniometer Radius: 185mm 
• Divergence Slit: 0.5°
• Receiving Slit Aperture: 0.15mm 
• Sollers Slit Acceptance Angle: 0.5° 
• Diffracted Beam Monochromator: flat graphite crystal 
• Start, Step, Stop: 10.06, 0.02, 120.04 
• Counting time: 30sec/step 
• Vertical Sample Holder: 20x20mm sample surface
• No spinning

• Filename: Zhu2.*
• Run on Siemens D501 
• Tube Type Siemens Cu FF
• Wavelengths: 1.54056 and 1.54439 A 
• Generator Power: 28mA, 38KV 
• Goniometer Radius: 200.5mm 
• Divergence Slit: 0.3° 
• Receiving Slit Aperture: 0.05° 
• Sollers Slit Acceptance Angle: 2°
• Diffracted beam curved graphite monochromator
• Start, Step, Stop: 10.00, 0.02, 130.04 
• Counting time: 24 seconds per point 
• Horizontal Sample Holder: 40 x 20mm sample surface 
• No Spinning

• Filename: zhu3.*
• Run on Siemens D501, 
• Tube Type Siemens Cu FF
• Wavelengths: 1.54056 and 1.54056 A 
• Generator Power: 28mA, 38KV 
• Goniometer Radius: 200.5mm 
• Divergence Slit: 1° 
• Receiving Slit Aperture: 0.15° 
• Sollers Slit Acceptance Angle: 2°
• Diffracted beam curved graphite monochromator
• Start, Step, Stop: 10.00, 0.02, 119.68 
• Counting time: 28 seconds per point. 
• Horizontal Sample Holder: 40 x 20mm sample surface
• No Spinning

Sample 2

Pharmaceutical :
From the Aldrich Chemical Company Inc.
Milwaukee, WI 53233 USA
Reference : 25,016-3     [64-75-5]
Tetracycline Hydrochloride 98%, 25g
Lot : TQ
No. : 14219PQ
For laboratory use only.

• Crystal system: orthorhombic 
• Cell : a = 10.981 A, b = 12.853 A,
  c = 15.733 A, 
• Space group : P2₁2₁2₁ 

• Conventional X-ray (Cu K-alpha) - Bragg Brentano 
• Capillary/Image-Plate system 

• Filename: aldxconv.*
• Run on Siemens D501 
• Tube Type Siemens Cu FF 
• Wavelengths: 1.54056 and 1.54439 A 
• Generator Power: 28mA, 38KV 
• Goniometer Radius: 200.5mm 
• Divergence Slit: 0.3° 
• Receiving Slit Aperture: 0.05° 
• Sollers Slit Acceptance Angle: 2° 
• Diffracted beam curved graphite monochromator 
• Start, Step, Stop: 10.06, 0.02, 120.04 
• Counting time: 48 sec./point 
• Horizontal Sample Holder: 40x20 mm sample surface
• No Spinning

• Filename: aldsync.* 
• Run on Graham Bushnell-Wye, et al. 
• Beam width and height: 0.5mmx0.5mm X-ray beam 
• Wavelength: 0.692 A 
• Distance from Sample to curved image plate: 350 mm 
• Start, Step, Stop: 2.115, 0.005, 40.000 
• Counting time: 5 hours 
• Sample Holder: Sample packed in 0.5mm glass capilliary, 
• References: 
• "Development of Curved Image-Plate Techniques for Studies of Powder Diffraction, Liquids and Amorphous Materials",

M.A. Roberts, J. L. Finney, G. Bushnell-Wye 
Proceedings of EPDIC-5, Parma, Italy, 1997. 
• "Developments and Time-Resolved Studies using a Curved Image-Plate Detector",

M.A. Roberts, J. L. Finney, G. Bushnell-Wye, W. A. Steer, Manuscript in Preparation.