K. Shankland, W.I.F. David, T. Csoka and L. McBride
Structure solution of Ibuprofen from powder diffraction
data by the application of a genetic algorithm combined
with prior conformational analysis
Int J Pharm 165 (1998) 117-126
Essentially, the structure solution process is accelerated
when torsional constraints derived from the Cambridge
Crystallographic Database are employed. A related paper
(Shankland et al, IJP 165 107-116) describes the prior
conformational analysis in full detail.
Best,
Kenneth
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Dr. Kenneth Shankland,ISIS Facility,Rutherford Appleton Laboratory
Chilton,Didcot,Oxon OX11 0QX,United Kingdom
Tel : +44 1235 44 6381
Fax : +44 1235 44 5720
E-Mail: k.shankland@rl.ac.uk
Date: 08-May-98
Time: 17:57:41
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